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Rev. gastroenterol. Perú ; 38(3): 297-300, jul.-set. 2018. ilus, tab
Article in Spanish | LILACS | ID: biblio-1014099

ABSTRACT

El coriocarcinoma gástrico primario (CGP) es un tumor extremadamente raro, altamente invasivo y de rápida diseminación hematógena. Presentamos el caso de una paciente de 57 años que inicia con cuadro de hematemesis y, progresivamente, se le suman episodios de melena, baja de peso y epigastralgia. Es derivada al Instituto Nacional de Enfermedades Neoplásicas en donde se le realizan gastroscopía y biopsia. Así, el análisis histológico reportó patrón sugestivo para CGP; el cual se confirmó al realizarle a la paciente los estudios por imágenes necesarios y llevar a cabo el análisis inmunohistoquímico para gonadotrofina coriónica humana y alfa feto proteína. Posteriormente, a la paciente se le realiza una gastrectomía radical D2 con preservación esplénica y de cola de páncreas. Lamentablemente, su evolución no fue favorable y fallece por la progresión de la enfermedad.


Primary gastric choriocarcinoma (PGC) is an extremely rare and highly invasive tumor with rapid hematogenous spread. We present the case of a 57-year-old female patient who started with hematemesis and progressive episodes of melena, weight loss and epigastralgia. It is derived from the National Institute of Neoplastic Diseases where gastroscopy and biopsy are performed. Histological analysis reported pattern suggestive of PGC; that was confirmed by immunohistochemical analysis for human chorionic gonadotrophin and fetal alpha protein. Subsequently, the patient underwent a radical D2 gastrectomy with splenic preservation and tail of the pancreas preservation. Unfortunately, her evolution was not favorable and died due to the progression of the disease.


Subject(s)
Female , Humans , Middle Aged , Stomach Neoplasms/pathology , Choriocarcinoma/pathology , Polyps/diagnosis , Polyps/pathology , Stomach Neoplasms/surgery , Stomach Neoplasms/diagnosis , Stomach Neoplasms/chemistry , Stomach Ulcer/etiology , Weight Loss , Adenocarcinoma/diagnosis , alpha-Fetoproteins/analysis , Choriocarcinoma/surgery , Choriocarcinoma/diagnosis , Choriocarcinoma/chemistry , Biomarkers, Tumor/analysis , Hematemesis/etiology , Melena/etiology , Gastroscopy , Fatal Outcome , Diagnosis, Differential , Gastrectomy/methods , Chorionic Gonadotropin/analysis
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